Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor tolebrutinib (SAR442168) (PERSEUS)

Trial Identifier: EFC16035
Sponsor: Sanofi
Start Date: August 2020
Primary Completion Date: November 2025
Study Completion Date: November 2025
Condition: Multiple Sclerosis (MS)

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

No documents have been posted yet.

Trial Locations

Country Location
Argentina, Buenos Aires CABA, Buenos Aires, Argentina, C1012AAR
Argentina, Santa Fe Rosario, Santa Fe, Argentina, 2000
Australia, New South Wales St Leonards, New South Wales, Australia, 2065
Australia, Tasmania Hobart, Tasmania, Australia, 7001
AUSTRALIA, New South Wales Concord, New South Wales, AUSTRALIA, 2139
AUSTRIA Linz, AUSTRIA, 4021
AUSTRIA Wien, AUSTRIA, 1090
Belarus Vitebsk, Belarus, 210037
Belarus Vitebsk, Belarus, 210009
Belgium Bruxelles, Belgium, 1070
Belgium Gent, Belgium, 9000
Belgium Liège, Belgium, 4000
Belgium Pelt, Belgium, 3900
Belgium Sint-Lambrechts-Woluwe, Belgium, 1200
BRAZIL, Paraná Curitiba, Paraná, BRAZIL, 81210-310
BRAZIL, São Paulo Sao Paulo, São Paulo, BRAZIL, 01228-000
Bulgaria Pleven, Bulgaria, 5809
Bulgaria Sofia, Bulgaria, 1113
Bulgaria Sofia, Bulgaria, 1431
Bulgaria Sofia, Bulgaria, 1407
Bulgaria Sofia, Bulgaria, 1606
Canada, Alberta Edmonton, Alberta, Canada, T6G 2C8
Canada, British Columbia Vancouver, British Columbia, Canada, V6T 2B5
Canada, Ontario Ottawa, Ontario, Canada, K1H 8L6
Canada, Quebec Montreal, Quebec, Canada, H2X 0A9
Canada, Quebec Montreal, Quebec, Canada, H3A 2B4
Canada, Quebec Quebec, Canada, G1W 4R4
CANADA, Ontario Hamilton, Ontario, CANADA, L8L 2X2
CANADA, Ontario Toronto, Ontario, CANADA, M5B 1W8
CANADA, Quebec Quebec, CANADA, G1J 1Z4
CANADA, Quebec Sherbrooke, Quebec, CANADA, J1H 5N4
Chile, Reg Metropolitana de Santiago Santiago, Reg Metropolitana de Santiago, Chile, 8380456
Chile, Reg Metropolitana de Santiago Santiago, Reg Metropolitana de Santiago, Chile, 7650568
China Beijing, China, 100032
China Beijing, China, 100730
China Beijing, China, 100053
China Changchun, China, 130021
China Changsha, China, 410008
China Chengdu, China, 610041
China Fuzhou, China, 350005
China Guangzhou, China, 510630
China hohhot, China, 010050
China Shanghai, China, 200040
China Taiyuan, China, 030001
China Wenzhou, China, 325000
COLOMBIA Bogota, COLOMBIA
COLOMBIA Bogotá, COLOMBIA, 111321
Croatia Zagreb, Croatia, 10000
Czech Republic Brno, Czech Republic, 65691
Czech Republic Hradec Kralove, Czech Republic, 50005
Czech Republic Jihlava, Czech Republic, 58633
Czech Republic Teplice, Czech Republic, 415 29
Denmark Esbjerg, Denmark, 6700
Denmark Holstebro, Denmark, 7500
ESTONIA Tallinn, ESTONIA, 11315
France BRON, France, 69500
France Clermont Ferrand, France, 63003
France Gonesse, France, 95500
France Lille, France, 59037
France Montpellier, France, 34295
France Nancy, France, 54035
France Nimes, France, 30029
France PARIS, France, 75019
France PARIS, France, 75013
France POISSY, France, 78300
France RENNES, France, 35033
France STRASBOURG, France, 67098
France TOULOUSE, France, 31059
Georgia Tbilisi, Georgia, 0160
Georgia Tbilisi, Georgia, 0172
Georgia Tbilisi, Georgia, 0114
GEORGIA Tbilisi, GEORGIA, 0159
Germany Bayreuth, Germany, 95445
Germany Berlin, Germany, 10713
Germany Bochum, Germany, 44791
Germany Dresden, Germany, 01307
Germany Gießen, Germany, 35385
Germany Hannover, Germany, 30625
Germany München, Germany, 81377
Germany Münster, Germany, 48149
Germany Ulm, Germany, 89081
GERMANY Berlin, GERMANY, 10117
GERMANY Düsseldorf, GERMANY, 40225
GERMANY Essen, GERMANY, 45147
GERMANY Rostock, GERMANY, 18055
Greece Athens, Greece, 11525
Greece Athens, Greece, 115 28
Greece Athens, Greece, 12462
Greece Larisa, Greece, 41110
Greece Maroussi, Greece, 15125
Greece Thessaloniki, Greece, 546 36
Greece Thessaloniki, Greece, 55236
Hungary Budapest, Hungary, 1083
Hungary Budapest, Hungary, 1033
HUNGARY Budapest, HUNGARY, 1138
India Bengaluru, India, 560001
India New Delhi, India, 110029
INDIA Mangaluru, INDIA, 575018
Israel Jerusalem, Israel, 91120
Israel Ramat Gan, Israel, 5266202
Israel Safed, Israel, 13100
Italy Chieti, Italy, 66100
Italy, Cagliari Cagliari, Italy, 09126
Italy, Catania Catania, Italy, 95123
Italy, Firenze Firenze, Italy, 50134
Italy, Isernia Pozzilli, Isernia, Italy, 86077
Italy, Milano Milano, Italy, 20132
Italy, Napoli Napoli, Italy, 80131
Italy, Not Known Napoli, Not Known, Italy, 80138
Italy, Roma Roma, Italy, 00189
Japan, Chiba Chiba-shi, Chiba, Japan, 260-8677
Japan, Fukushima Koriyama-shi, Fukushima, Japan, 963-8052
Japan, Kyoto Kyoto-shi, Kyoto, Japan, 616-8255
Japan, Miyagi Sendai-shi, Miyagi, Japan, 980-8574
Japan, Niigata Niigata-shi, Niigata, Japan, 951-8520
Japan, Osaka Moriguchi-shi, Osaka, Japan, 570-8507
Japan, Osaka Osaka-shi, Osaka, Japan, 556-0016
Japan, Saitama Kawagoe-shi, Saitama, Japan, 350-8550
Japan, Tokyo Bunkyo-ku, Tokyo, Japan, 113-8431
Japan, Tokyo Shinjuku-ku, Tokyo, Japan, 160-8582
Japan, Toyama Toyama-shi, Toyama, Japan, 930-0194
JAPAN, Iwate Morioka-shi, Iwate, JAPAN, 020-8505
JAPAN, Kanagawa Sagamihara-shi, Kanagawa, JAPAN, 252-0392
JAPAN, Tokyo Kodaira-shi, Tokyo, JAPAN, 187-8551
JAPAN, Tokyo Ota-ku, Tokyo, JAPAN, 146-0065
Latvia Riga, Latvia, LV-1002
Mexico, Not Known Tlalnepantla, Not Known, Mexico, 54055
MEXICO, Jalisco Guadalajara, Jalisco, MEXICO, 44670
MEXICO, México CDMX, México, MEXICO, 06700
MEXICO, México Mexico city, México, MEXICO, 14050
MEXICO, Veracruz Veracruz, MEXICO, 91910
Netherlands Breda, Netherlands, 4818 CK
Netherlands Groningen, Netherlands, 9728NT
Netherlands Sittard-Geleen, Netherlands, 6162 BG
Norway Bergen, Norway, 5021
Norway Tromsø, Norway, 9038
Peru LIMA, Peru, 15084
Poland, Lódzkie Lodz, Lódzkie, Poland, 90-549
Poland, Mazowieckie Warszawa, Mazowieckie, Poland, 01-684
Poland, Slaskie Katowice, Slaskie, Poland, 40-686
POLAND, Kujawsko-pomorskie Bydgoszcz, Kujawsko-pomorskie, POLAND, 85-796
POLAND, Mazowieckie Warszawa, Mazowieckie, POLAND, 01-211
POLAND, Slaskie Katowice, Slaskie, POLAND, 40-684
Portugal Braga, Portugal, 4710-243
Portugal Lisboa, Portugal, 1349-019
Portugal Lisboa, Portugal, 1500-650
Portugal Matosinhos, Portugal, 4464-513
Portugal Porto, Portugal, 4099-001
PORTUGAL Santa Maria da Feira, PORTUGAL, 4520-211
Romania Bucuresti, Romania, 022328
Romania Campulung Muscel, Romania, 115100
Romania Constanta, Romania, 900123
Romania Oradea, Romania, 410154
Romania Targu Mures, Romania, 540136
Romania TIMIȘOARA, Romania, 300736
Russian Federation Ekaterinburg, Russian Federation, 620102
Russian Federation Moscow, Russian Federation, 129128
Russian Federation Nizhny Novgorod, Russian Federation, 603137
Russian Federation Pyatigorsk, Russian Federation, 357538
Russian Federation Rostov-on-Don, Russian Federation, 344022
Russian Federation Samara, Russian Federation, 443095
Russian Federation Saransk, Russian Federation, 430032
Russian Federation Tyumen, Russian Federation, 625000
Russian Federation Ufa, Russian Federation, 450005
RUSSIAN FEDERATION Barnaul, RUSSIAN FEDERATION, 656043
RUSSIAN FEDERATION Kaliningrad, RUSSIAN FEDERATION, 236035
RUSSIAN FEDERATION Kazan, RUSSIAN FEDERATION, 420032
RUSSIAN FEDERATION Krasnoyarsk, RUSSIAN FEDERATION, 660029
RUSSIAN FEDERATION Moscow, RUSSIAN FEDERATION, 117997
RUSSIAN FEDERATION Saint-Petersburg, RUSSIAN FEDERATION, 197376
Serbia Belgrade, Serbia, 11000
Serbia Kragujevac, Serbia, 34000
South Africa Pretoria, South Africa, 0041
Spain, A Coruña [La Coruña] La Coruña, A Coruña [La Coruña], Spain, 15006
Spain, A Coruña [La Coruña] Santiago de Compostela, A Coruña [La Coruña], Spain, 15706
Spain, Andalucia Sevilla, Andalucia, Spain, 41009
Spain, Barcelona [Barcelona] Barcelona, Barcelona [Barcelona], Spain, 08035
Spain, Bizkaia Bilbao, Bizkaia, Spain, 48013
Spain, Córdoba Córdoba, Spain, 14004
Spain, Girona [Gerona] Salt, Girona [Gerona], Spain, 17190
Spain, Las Palmas Las Palmas de Gran Canaria, Las Palmas, Spain, 35010
Spain, Madrid Madrid, Spain, 28007
Spain, Madrid Majadahonda, Madrid, Spain, 28222
Spain, Madrid Pozuelo De Alarcón, Madrid, Spain, 28223
Spain, Murcia Murcia, Spain, 30120
Spain, Not Known Malaga, Not Known, Spain, 29010
Spain, Not Known Palma de Mallorca, Not Known, Spain, 07120
Spain, Valencia Valencia, Spain, 46026
Sweden Göteborg, Sweden, 413 45
Sweden Motala, Sweden, 591 85
Thailand Bangkok, Thailand, 10700
Turkey Izmir, Turkey, 35340
Turkey Konya, Turkey, 42080
TURKEY Ankara, TURKEY, 06500
TURKEY Ankara, TURKEY, 06100
TURKEY Eskisehir, TURKEY, 26040
TURKEY Hatay, TURKEY
TURKEY Istanbul, TURKEY, 34265
TURKEY Istanbul, TURKEY, 34303
TURKEY Istanbul, TURKEY, 34093
TURKEY Istanbul, TURKEY, 34785
TURKEY Izmir, TURKEY, 35100
TURKEY Izmit, TURKEY, 41380
TURKEY Kutahya, TURKEY, 43100
TURKEY Mersin, TURKEY, 33070
TURKEY Samsun, TURKEY
Ukraine Kharkiv, Ukraine, 61103
Ukraine Kharkiv, Ukraine, 61068
Ukraine Kyiv, Ukraine, 01135
Ukraine Kyiv, Ukraine, 02091
Ukraine Lutsk, Ukraine, 43005
Ukraine Lviv, Ukraine, 79010
Ukraine Odesa, Ukraine, 65025
Ukraine Vinnytsya, Ukraine, 21001
UKRAINE Chernivtsi, UKRAINE, 58023
UKRAINE Ivano-Frankivsk, UKRAINE, 76493
UKRAINE Kharkiv, UKRAINE, 61068
UKRAINE Kyiv, UKRAINE, 03115
UKRAINE Lviv, UKRAINE, 79013
United Kingdom, Devon EXETER, Devon, United Kingdom, EX2 5DW
United Kingdom, Kent Canterbury, Kent, United Kingdom, CT1 3NG
United Kingdom, London, City of London, London, City of, United Kingdom, EC1M 6BQ
United Kingdom, Not Known Bristol, Not Known, United Kingdom, BS10 5NB
United Kingdom, Salford Salford, United Kingdom, M6 8HD
UNITED KINGDOM, London, City of London, London, City of, UNITED KINGDOM, SW17 0QT
UNITED KINGDOM, Neath Port Talbot Swansea, Neath Port Talbot, UNITED KINGDOM, SA6 6NL
UNITED KINGDOM, Nottinghamshire Nottingham, Nottinghamshire, UNITED KINGDOM, NG7 2UH
UNITED KINGDOM, Oxfordshire Oxford, Oxfordshire, UNITED KINGDOM, OX3 9DU
UNITED KINGDOM, Sheffield Sheffield, UNITED KINGDOM, S5 7AU
UNITED KINGDOM, Vale of Glamorgan, The Cardiff, Vale of Glamorgan, The, UNITED KINGDOM, CF4 4XY
United States, California Los Angeles, California, United States, 90033
United States, California San Francisco, California, United States, 94158
United States, Florida Maitland, Florida, United States, 32761
United States, Florida Tampa, Florida, United States, 33612
United States, Illinois Northbrook, Illinois, United States, 60062
United States, Louisiana New Orleans, Louisiana, United States, 70121
United States, Maryland Lutherville, Maryland, United States, 21093
United States, Michigan Owosso, Michigan, United States, 48867
United States, North Carolina Durham, North Carolina, United States, 27710
United States, North Carolina Raleigh, North Carolina, United States, 27607
United States, Ohio Columbus, Ohio, United States, 43221
United States, Texas San Antonio, Texas, United States, 78258
UNITED STATES, California La Jolla, California, UNITED STATES, 92037
UNITED STATES, California Los Alamitos, California, UNITED STATES, 90720
UNITED STATES, California Newport Beach, California, UNITED STATES, 92663
UNITED STATES, California Pasadena, California, UNITED STATES, 91105
UNITED STATES, California Torrance, California, UNITED STATES, 90502
UNITED STATES, California West Hollywood, California, UNITED STATES, 90048
UNITED STATES, Colorado Fort Collins, Colorado, UNITED STATES, 80528
UNITED STATES, Florida Boca Raton, Florida, UNITED STATES, 33487
UNITED STATES, Florida Clearwater, Florida, UNITED STATES, 33761
UNITED STATES, Florida Gainesville, Florida, UNITED STATES, 32601
UNITED STATES, Georgia Savannah, Georgia, UNITED STATES, 31406
UNITED STATES, Hawaii Honolulu, Hawaii, UNITED STATES, 96817
UNITED STATES, Indiana Merrillville, Indiana, UNITED STATES, 46410
UNITED STATES, Kansas Overland Park, Kansas, UNITED STATES, 66210
UNITED STATES, Kentucky Lexington, Kentucky, UNITED STATES, 40536
UNITED STATES, Massachusetts Boston, Massachusetts, UNITED STATES, 02111
UNITED STATES, Massachusetts Worcester, Massachusetts, UNITED STATES, 01655
UNITED STATES, Michigan Farmington Hills, Michigan, UNITED STATES, 48334
UNITED STATES, Minnesota Rochester, Minnesota, UNITED STATES, 55905
UNITED STATES, Missouri Ozark, Missouri, UNITED STATES, 65721
UNITED STATES, Nebraska Omaha, Nebraska, UNITED STATES, 68198
UNITED STATES, New Jersey Hackensack, New Jersey, UNITED STATES, 07601
UNITED STATES, New Mexico Albuquerque, New Mexico, UNITED STATES, 87131
UNITED STATES, New York New York, UNITED STATES, 10029-6501
UNITED STATES, New York Stony Brook, New York, UNITED STATES, 11794
UNITED STATES, North Carolina Winston-Salem, North Carolina, UNITED STATES, 27103
UNITED STATES, Ohio Cincinnati, Ohio, UNITED STATES, 45212
UNITED STATES, Ohio Cleveland, Ohio, UNITED STATES, 44195
UNITED STATES, Ohio Columbus, Ohio, UNITED STATES, 43235
UNITED STATES, Oregon Portland, Oregon, UNITED STATES, 97225
UNITED STATES, Pennsylvania Philadelphia, Pennsylvania, UNITED STATES, 19107
UNITED STATES, South Carolina Greer, South Carolina, UNITED STATES, 29651-1817
UNITED STATES, Texas Katy, Texas, UNITED STATES, 77450